Laboratory Testing To Assess Fetal Lung Maturity
نویسندگان
چکیده
منابع مشابه
Fetal lung maturity testing.
Hyaline membrane disease (HMD) is a disorder primarily affecting premature infants and is a significant cause of morbidity and mortality in this population. The disorder is characterized by widespread atelectasis and an inability of the neonate to expand his or her lungs. Secondary hemor rhage, edema and desquamation of alveolar lining cells then occur which further compromise respira tory func...
متن کاملCost-effectiveness of fetal lung maturity testing in preterm labor.
OBJECTIVE To determine the marginal cost-effectiveness of two strategies for preventing respiratory distress syndrome (RDS) resulting from preterm birth: 1) tocolysis with beta-mimetic agonists and treatment with corticosteroids (TREATALL), and 2) amniocentesis and testing for fetal lung maturity, with treatment based on test results (TESTALL), compared with no treatment. METHODS We used a Ma...
متن کاملRadial "high-performance" thin-layer chromatography used to assess fetal lung maturity.
A radial "high-performance" thin-layer chromatographic (HPTLC) method is described by which the percentages and ratios of phosphatidylinositol, sphingomyelin, lecithin, phosphatidylethanolamine, phosphatidylglycerol, and dimethyl phosphatidylethanolamine may be determined simultaneously. An additional method for radial HPTLC determination of saturated phosphatidylcholine is described. We report...
متن کاملBiochemical assessment of fetal lung maturity.
The relationship between the enzyme phosphatidate phosphohydrolase (PAPase) and lecithin/sphingomyelin (L/S) ratio in amniotic fluid was evaluated in normal human pregnancies and in several pregnancies complicated by Rh isoimmunization. An increase in PAPase activity in amniotic fluid appears to parallel the increase in L/S ratio after 33 weeks gestation in normal subjects. These data suggest t...
متن کاملRoutine diagnosis of fetal lung maturity.
The respiratory distress syndrome (RDS) is the most frequent postnatal complication of prematurity having a 25% lethal outcome even today (KEUTH [6]). The same author reports that RDS affects 8% of an unselected population of premature infants and 20% of a negatively selected population found in clinical departments for premature babies. Hence avoidance of prematurity is one of the most importa...
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ژورنال
عنوان ژورنال: Laboratory Medicine
سال: 2001
ISSN: 0007-5027,1943-7730
DOI: 10.1309/h6w4-vm9q-cvgt-ujgl